or In particular its been disappointing to see the limited impact of sequencing on SARS-CoV2 diagnostics. Ive worked for a few sequencing companies. BGI countersuedmonths later. With these players appearing, with a similar data quality, and a similar error profile, I expect that many users will be able to switch platforms if they want. Illumina was represented by Colm Murphy, London partner of US law firm Cooley. Statistics cookies collect information anonymously. Well, for a start I expect it to put downward pressure on Illuminas consumable pricing. hb```v eah`hje0sDt'j;:*:::$ np4p&~P%CH@| .Hibe`1Fq10f@$` !1
This broadening of the market sucks for Illumina. Cookie by Google used to control advanced script and event handling. I have equity in a few sequencing companies based on my previous employment (I try to be unbiased in my posts). Accept all The latter represented Qiagen in one of the proceedings. The nearly $1 million Novaseq 6000 is expected to one day unlock the $100 genome. An Illumina spokesperson said the company disagrees with the verdict and plans to appeal. The Court found that four of the five asserted patents were valid and . For the global patent community. Generates statistical data on how the visitor uses the website. So if youd be interest in investing in (or codeveloping) such a platform, get in touch. Scripts to download SARS-CoV-2 replacements, Sony CCD-V8AF Video Camera Recorder Viewfinder CRT Notes, Playing with a Handycam CCD-F340 Viewfinder CRT Notes, Thoughts on a new approach to viral testing, Quick script to download Uniprot info for proteins from Pfam trees (Newick tree format), Notes on fixing a broken Gentoo grub install, Notes on using a ILX511 Linear CCD, AD9225 ADC, ICE40HX8K and Nmigen, Thoughts on interviewing with YC as a science based startup, 2018 DNA Sequencing Raises and Acquisitions. The patents in that case expire in August 2022 and January 2023. Illumina Pays To Settle Years-Long Patent Battles, Investors Withdraw $6B From Binance Amid Crypto Regulation, Meta Offers New Options For Researchers Working In Artificial Intelligence, Microsoft, Activision Deal Review Extended By The European Commission, Microsoft Drastically Scales Back Metaverse Project, Focuses On AI, Bill That Aims To Block TikTok Approved By US House Panel, EU: Google promotes rivals to stave off antitrust action. "BGI has brazenly copied Illumina's proprietary sequencing chemistry. Competitors in this market include the German company Qiagen and the Chinese manufacturer of genetic sequencers BGI Group, as well as MGI. And I suspect companies like Element are working on something similar. Many of the cases have settled, though some remain under appeal. by You can give your consent to whole categories or display further information and select certain cookies. You can find out more about which cookies we are using or switch them off in settings. df-mp Drries Frank-Molnia & Pohlman Patentanwlte Rechtsanwlte PartG mbB, filed apatent infringement counterclaim against Illumina, https://policies.google.com/privacy?hl=en, https://www.hotjar.com/legal/policies/privacy/, https://www.facebook.com/privacy/explanation, https://policies.google.com/privacy?hl=en&gl=en, https://wiki.osmfoundation.org/wiki/Privacy_Policy. Law360 may contact you in your professional capacity with information about our other products, services and events that we believe may be of interest.Youll be able to update your communication preferences via the unsubscribe link provided within our communications.We take your privacy seriously. You can give your consent to whole categories or display further information and select certain cookies. Illumina has won a patent infringement suit in the UK against defendant MGI over DNA sequencing technology. The stock closed Friday up 7.4. Tesla recalls 3,470 Model Y vehicles over loose bolts, Exclusive: Nvidia's plans for sales to Huawei imperiled if U.S. tightens Huawei curbs-draft, Reporting by Blake Brittain in Washington; additional reporting by Raghavi Kasa; Editing by David Gregorio and Diane Craft, Mexico can't match U.S. incentives for proposed Tesla battery plant, minister says, Taiwan's TSMC to recruit 6,000 engineers in 2023, Twitter's revenue, adjusted earnings drop about 40% in December - WSJ, Exclusive news, data and analytics for financial market professionals. Browse an unrivalled portfolio of real-time and historical market data and insights from worldwide sources and experts. Screen for heightened risk individual and entities globally to help uncover hidden risks in business relationships and human networks. Previously, Illumina said that US Patent No. You can revoke or adjust your selection at any time under Settings. Imprint. Illumina has. European patent attorney Philippa Griffin of Mathys & Squire appeared as a strawman in the appeal hearing. But in May, a Delaware jury decided that Illumina owes Complete Genomics more than $333 million for infringing on two patents, court documents state. In 2010, Illumina filed a complaint in California against Complete Genomics, an MGI subsidiary, alleging that the company infringed on three of its DNA sequencing patents with the latter companys Complete Genomics Analysis Platform. In response, Complete Genomics asserted that Illumina had attempted to achieve monopoly power in genome sequencing technology.. The company also filed an anticompetitive suit against Illumina in Delaware last year. Opponents included strawmen as well as Qiagen, a Germany-based provider of DNA sequencing technology. Illumina innovative sequencing and array technologies are fueling groundbreaking advancements in life science research, translational and consumer genomics, and molecular diagnostics. Hardware (Instrument) Hardware will conform to Illumina's specifications for 12 months after shipment from Illumina. endstream
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It is Illumina's policy to seek patent protection in the United States and abroad for such technology and products. How the biggest companies plan mass lay-offs, The benefits of revealing neurodiversity in the workplace, Tim Peake: I do not see us having a problem getting to Mars, Our ski trip made me question my life choices, Michelle Yeoh: Finally we are being seen, Apocalypse then: lessons from history in tackling climate shocks, How Glasgows tiny, muckraking crime mag stays afloat, Smart data to help spot risk and opportunity, Lex, our agenda-setting business commentary (Premium only), Due Diligence, an exclusive M&A newsletter (Premium only). cookies In the legal profession, information is the key to success. This website uses cookies so that we can provide you with the best user experience possible. If you do nothing, you will be auto-enrolled in our premium digital monthly subscription plan and retain complete access for $69 per month. But how else will they respond? The jury also ruled that three Illumina patents in the case were invalid. The jury's verdict follows the decision of Judge William Orrick, in the same case, to award Illumina summary judgment on claims of infringement by BGI's StandardMPS and CoolMPS products. The listed products and their use are the subject of the following US Patent Nos. Are there mutations in SARS-CoV-2 CDC qPCR Primer Sites? Refuse. Some of them are essential, while others help us to improve this website and your experience. Im not a patent lawyer, so you should consider that when evaluating my thoughts. 7,566,537 and 9,410,200. Back in November, a federal jury ruled that four of Illumina's five patents in the California case were valid, awarding it $8 million, according to a Law360 report. 287 (a) for the following products: Last Updated: 2022-06-23 As a result, companies are now fighting hard for market share in this cutting-edge technology. Address of host server location: 5200 Illumina Way, San Diego, CA 92122 U.S.A. All trademarks are the property of Illumina, Inc. or their respective owners. 258 0 obj
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offers FT membership to read for free. We use cookies and other technologies on our website. 7, 771,973, titled "modified nucleotides" will expire in August 2022. As a global company that places high value on collaborative interactions, rapid delivery of solutions, and providing the highest level of quality, we strive to meet this challenge. original cluster generation IP has expired (from Manteia) has expired. The decision related to five of Illumina's patents for DNA sequencing technology: three of the patents (all divisionals) related to azidomethyl groups as reversible chain terminators ("RCTs") in sequencing by synthesis ("the modified nucleotide patents"); the fourth patent related to the use of ascorbic acid as a component in the . 0
Hotjar is an user behavior analytic tool by Hotjar Ltd.. We use Hotjar to understand how users interact with our website. Premium Digital includes access to our premier business column, Lex, as well as 15 curated newsletters covering key business themes with original, in-depth reporting. New Study: China Overtakes US In Competition For Key Emerging Tech, Mexico Issues Highest-Ever Gun-Jumping Penalty. If youd like to retain your premium access and save 20%, you can opt to pay annually at the end of the trial. The jury, which started deliberating Thursday afternoon, also found that sequencers sold by BGIs Complete Genomics Inc. infringe two of three Illumina patents, but it said all three shouldnt have been issued in the first place, mooting any potential award, according to the verdict issued in the U.S. District Court for the District of Delaware. A technician uses an Illumina Inc. DNA sequencing machine at the Li Ka Shing Institute of Health Sciences at the Chinese University of Hong Kong in Hong Kong, China, on June 20, 2017. The European patent attorney also regularly files patents for the US company at theEPO. %%EOF
They do this by tracking visitors across websites. According to Illumina, the '444 patent was set to expire in June 2023 and US Patent No. Hide Cookie Information. Get U-T Business in your inbox on Mondays. So I imagine what theyll do is reduce pricing so that theyre competitive but not the cheapest option. | N choose K, with T targets. Some of them are essential, while others help us to improve this website and your experience. Illumina MiSeq Dx Cystic Fibrosis Assays, TruSeq Stranded total RNA Sample Prep Kits, BaseSpace Cohort Analyzer Related Products, BaseSpace Variant Interpreter Related Products, BaseSpace Correlation Engine Related Products. As of right now, it seems that Illumina's original cluster generation IP has expired (from Manteia) has expired. So the cluster and nucleotide IP are really the key to producing an Illumina-style DNA sequencer. 2023 Illumina, Inc. All rights reserved. REUTERS/Mike Blake. The patent covers a DNA sequencing method. Illumina is forking over the $325 million to settle claims following two recent jury decisions in Delaware and California, as well as an antitrust case in California, according to a statement on Thursday from MGI Tech, a BGI affiliate. travels to Asia to strengthen business ties, How major US stock indexes fared Friday 3/3/2023, VMware, Broadcom rise; Marvell, Bumble fall. Navigating the New Matchmaker Economy David S. Evans at George Washington U. The companies have been embroiled in a global legal battle over their respective sequencing technologies, with court cases in countries including Germany, Denmark, Switzerland, and Turkey. New configurations will bring longer read capabilities with more output for immune repertoire, shotgun metagenomics and more, Discover novel trait and disease associations with optimized tag SNPs and functional exonic content at an attractive price, DRAGEN v4.0 release enables machine learning by default, providing increased accuracy out of the box, Our instrument performance service helps reduce unplanned downtime and minimize instrument requalification, Robust methylation profiling microarray with extensive coverage of CpG islands, genes, and enhancers, Two DRAGENs help Cardio-CARE slay one petabyte of data to better understand heart disease in Hamburg, Together, were finding answers to lifes biggest questions and broadening the positive impact of genomics around the world, Get instructions for using Illumina DRAGEN Bio-IT Platform v4.0, Enable comprehensive genomic profiling with accurate and comprehensive homologous recombination deficiency assessment, Save on the Ribo-Zero Plus Microbiome rRNA Depletion Kit, restrictions apply, A multi-species, low-cost, genome-wide genotyping platform to support molecular breeding in small grains, A comprehensive, easy-to-implement, and versatile genomic analysis tool set for translational researchers, The NovaSeq 6000Dx is our first IVD-compliant high-throughput sequencing instrument for the clinical lab. The buyer cannot sell or otherwise transfer this product or its components to a third party or otherwise use the product for the following COMMERCIAL PURPOSES: (I) use of the product or its components in manufacturing; or (2) use of the product or its components for therapeutic or prophylactic purposes in humans or animals. Retailer Reg: 2019--2018 | Illumina Inc.owes BGI Group, the world's largest maker of commercial genetic sequencers, $333.8 million after a federal jury in Delaware found Friday that some of its DNA sequencing systems infringe two patents related to technology that deduces each nucleotide's identity from two signals. The jury also said Illumina infringed the patents willfully, and that three patents it had accused BGI's Complete Genomics unit of infringing were invalid. Limited Use Label License: This product and its use are the subject of one or more issued and/or pending US and foreign patent applications owned by Max Planck Gesellschaft, exclusively licensed to New England Biolabs, Inc. and sublicensed to Illumina, Inc. Probability of choosing at least one target, Ubuntu 20.04 Fujitsu FAREHT1 Mouse/Touch Screen Fixes, Beckman DU530 Spectrophotometer CFL Spectra, Beckman DU530 Photospectrometer (Hach DR4000?) IP addresses), for example for personalized ads and content or ad and content measurement. hbbd```b`` Any changes made can be done at any time and will become effective at the end of the trial period, allowing you to retain full access for 4 weeks, even if you downgrade or cancel. See here for a complete list of exchanges and delays. Additionally, Natera has granted Illumina a non-exclusive license to Natera's '592 Patent family. 229 0 obj
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This information helps us to understand how our visitors use our website. Our Standards: The Thomson Reuters Trust Principles. Illumina's '973 patent is expected to expire in 2023 and the '444 patent in 2024. DNA Sequencing is Universal Sensing, Mitutoyo Digimatic 500-133U CDL-6B Battery Cover Model, NEC Teledata Terminal Shop Register (TD7), Motorboard Easydriver/Arduino/PKE243DA interface r1, Veeco Nanoscope V Multimode AFM First Imaging Tests, Axopatch 200A with micropipette first tests, Playing with a micropipette puller (Sutter P-97), Couldnt remount RDWR because of unprocessed orphan inode list. ), Illumina Win Over BGI Upheld as Judge Blocks Gene Sequencers (2), Illumina, BGI Trim Patent Claims as Another Jury Trial Looms, BGI Asks For New Patent Trial After $8 Million Loss to Illumina, BGI Must Pay Illumina $8 Million in Gene-Sequencing Patent Spat, Complete Genomics Inc. v. Illumina Inc. (D. He said the company is also pleased that the jury invalidated the cases three Illumina patents. The Biden administration is close to tightening rules on some overseas investments by American companies, A Volkswagen Group-backed automotive company announced plans this week to open a $2 billion electric truck and SUV manufacturing plant just outside of Columbia, South Carolina, Oklahoma voters are deciding whether to legalize marijuana sales for those 21 and older. All were invalidated in Fridays verdict. A jury recently invalidated Illumina's U.S. Patent No. Griffins clients include New England Biolabs and the Ecole Polytechnique Fdrale De Lausanne (EPFL). All quotes delayed a minimum of 15 minutes. Illumina also said Friday in a filing with the U.S. Securities & Exchange Commission that it may have to pay interest and an ongoing royalty until the patents expire in 2029 if it loses on appeal. qPCR dominates here because the COGS for qPCR is essentially $1 and the COGS or instruments a few hundred. Personal data may be processed (e.g. Not for import or sale to the Australian general public. Some was asking on Twitter about the effect of Illuminas IP expiring on the sequencing industry. 10,480,025 (the '025 Patent) asserted against BGI in the suit, which are directed to blocked other approaches on the market or in development. You can find more information about the use of your data in our privacy policy. From Europe. See here for a complete list of exchanges and delays. (This story corrects statement in paragraph 1 that Complete Genomics is a subsidiary of BGI Genomics to reflect that it is part of BGI Group). Harrods chief shrugs off recession fears because rich get richer, FCA regulator blamed for Arms decision to shun London listing, Argentina diary: Come armed with $100 bills, There are no domestic equity investors: why companies are fleeing Londons stock market, Clutching Warrens letter, Im still positive on stocks, The Murdaugh trial: a southern gothic tale that gripped the nation, Humanity is sleepwalking into a neurotech disaster, Who to fire? It is mission critical for us to deliver innovative, flexible, and scalable solutions to meet the needs of our customers. Show Cookie Information Here you will find an overview of all cookies used. Try full digital access and see why over 1 million readers subscribe to the FT, Purchase a Trial subscription for $1 for 4 weeks, You will be billed $69 per month after the trial ends, Russian far-right fighter claims border stunt exposes Putins weakness, Something is boiling: Turkish football fans tackle Erdoan, Three-day weekends and more time for love: Chinas elite dream up policies for Xi, Germany and Italy stall EU ban on combustion engines, Feds Daly says US rates likely to be higher for longer, Saudi owner of Londons most expensive house sued over alleged unpaid private jet bills, Why the Jeffrey Epstein scandal continues to haunt JPMorgan and Barclays, US electric vehicle batteries poised for new lithium iron age. 249 0 obj
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Content from video platforms and social media platforms is blocked by default. This latest settlement should put an end to the storm of lawsuits at least for a while. Reach him at blake.brittain@thomsonreuters.com. Illumina Inc. owes BGI Group, the world's largest maker of commercial genetic sequencers, $333.8 million after a federal jury in Delaware found Friday that some of its DNA sequencing systems infringe two patents related to technology that deduces each nucleotide's identity from two signals. If you are under 16 and wish to give consent to optional services, you must ask your legal guardians for permission. 7,375,234; 7,763,736; 8,129,542; 8,580,970; 8,877,939 and related patents and patent applications. David Bilsker, a lawyer from Quinn Emanuel Urquhart & Sullivan LLP who represented Complete Genomics, said the jurys findings shows the strength of Rade Drmanacs inventions. Illumina invented its 2-channel technology before the BGI patents, and BGI was unable to make 2-channel chemistry work until it copied Illuminas technology, the spokesperson said in a statement. Back in November, a federal jury ruled that four of Illuminas five patents in the California case were valid, awarding it $8 million, according to a Law360 report. Cooley (London): Colm Murphy, For Qiagen and as a strawman If you disable this cookie, we will not be able to save your preferences. But I think whats really more interesting to me are approaches that reduce the COGS. In addition, although Complete Genomics may seek an injunction, we do not believe there is a reasonable basis for the court to grant one, said Illumina in the filing. Illumina, or (ii) any expiration date or the end of the shelf-life pre-printed on the consumable, but in either event, no later than 12 months from the date of shipment. Except Illumina dont make much money that way. Reuters, the news and media division of Thomson Reuters, is the worlds largest multimedia news provider, reaching billions of people worldwide every day. Illumina have a number of polymerase patents. How much does it cost to ship 1cm^2 of silicon? Orrick also issued a permanent injunction blocking BGI from selling CoolMPS products in the U.S. until after Aug. 23, when the only valid patent at issue against that sequencer will have expired. In addition, the EPO revoked patents EP 2 338 893 and EP 1 451 351 B1from a patent family for labelled nucleotides. Q. Those patents werent part of the Delaware case. BGI Group is the corporate parent of both MGI, Complete Genomics owner, and of BGI Genomics. Law360, San Francisco (November 30, 2021, 11:16 PM EST) -- A California federal jury determined Tuesday that four out of five of Illumina 's patents behind its next-generation genome-sequencing . If its appeal is unsuccessful, Illumina could be required to pay an ongoing royalty until the patents expire in 2029, the company said in a filing with the U.S. Securities and Exchange Commission. Personal data may be processed (e.g. The patents in that case expire in August 2022 and January 2023. Privacy Policy As I understand it with that IP alone you could make something that looks very much like a genome analyzer 2. In a later Delaware case, Complete Genomics accused Illumina of infringing on its own patents with two-channel sequencing systems, kits to prepare DNA fragments for sequencing and kits to immobilize, amplify and sequence fragments. Password (at least 8 characters required). Please see our Privacy Policy. endstream
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Systems and methods for biochemical analysis including a base instrument and a removable cartridge, Methods and compositions for whole genome amplification and genotyping, BASE CALLING USING THREE-DIMENTIONAL (3D) CONVOLUTION, DEEP LEARNING-BASED SPLICE SITE CLASSIFICATION, Compositions for use in polynucleotide sequencing, LAMINATE FLUIDIC CIRCUIT FOR A FLUID CARTRIDGE, DEEP NEURAL NETWORK-BASED VARIANT PATHOGENICITY PREDICTION, POLYMERASES, COMPOSITIONS, AND METHODS OF USE, Charge-tagged nucleotides and methods of use thereof, Photonic structure-based devices and compositions for use in luminescent imaging of multiple sites within a pixel, and methods of using the same, Flowcell cartridge with floating seal bracket, SEMICONDUCTOR-BASED BIOSENSORS FOR BASE CALLING, BASE CALLING USING MULTIPLE BASE CALLER MODELS, DEEP LEARNING-BASED USE OF PROTEIN CONTACT MAPS FOR VARIANT PATHOGENICITY PREDICTION, TRANSFER LEARNING-BASED USE OF PROTEIN CONTACT MAPS FOR VARIANT PATHOGENICITY PREDICTION, QUALITY SCORE CALIBRATION OF BASECALLING SYSTEMS. The reversible terminator IP has not they're currently using this IP to block the sale of some MGI instruments. According to MGIs statement:The parties also agree to a three-year period of peace with respect to claims of U.S. patent infringement and violations of any antitrust or unfair competition laws of the United States, during which time they will not sue each other or respective customers in the United States or accrue liability for existing platforms.. You may occasionally receive promotional content from the San Diego Union-Tribune. Then everyone buys Illumina sequencers because they have the lowest cost and highest quality! Even with multiplexing sequencing cant yet approach this. A Delaware federal jury decided Friday that Illumina willfully infringed two Complete Genomics Inc. DNA sequencing patents and should pay $334 million in damages, while also invalidating three . personalising content and ads, providing social media features and to It has the same estimated expiration as the first patent. If you are under 16 and wish to give consent to optional services, you must ask your legal guardians for permission. According to an exhibitfiled with the complaint, Illumina said a BioRxivpreprintposted Feb. 20 proved CoolMPS technology infringed the '973 patent. But it will be short lived. In late March, a federal judge in San Francisco upheld a jurys November verdict awarding Illumina $8 million for BGI Genomics infringement of at least one valid claim in three of the five genetic-sequencing patents at issue. At the very least MGI will be unblocked from selling instruments in the US. For a full comparison of Standard and Premium Digital, click here. Want more news? It also bars U.S. sales of StandardMPS products through Jan. 21, 2023. Whats your favorite San Diego County beach? SAN DIEGO-- (BUSINESS WIRE)-- Illumina, Inc. (NASDAQ: ILMN) today announced that the High Court of Justice, Chancery Division, Patents Court, issued a judgment in its favor in the patent infringement suit filed against the BGI Companies, MGI Tech Co. Ltd; Latvia MGI SIA; MGI International Sales Co., Ltd; and BGI Complete Genomics Hong Kong Co., In this case, the jury found Illumina willfully infringed on BGI/Complete Genomics patents related to two-channel techniques used in genomics sequencing. For specific trademark information, see www.illumina.com/company/legal.html. For Illumina Can Shell close the valuation gap with US rivals? and its possible those markets might grow. Theyre iterated over the original IP pretty well and have a number of other advantages over new players specifically: This is all technology was developed for Hiseqs and later instruments. If External Media cookies are accepted, access to those contents no longer requires manual consent. We are using cookies to give you the best experience on our website. But my understanding is that the 9N (9 degrees North) and related polymerases incorporate modified nucleotides pretty well. Gene sequence giant Illumina is weighing its next moves after a federal jury in Delaware found the San Diego company infringed on two patents from a rival genomics company and awarded $334 million in damages. Host: https://www.illumina.com | At the moment there doesnt seem to be any effective competition to Illumina. So I dont expect some huge shake up here. The latest of these patents is due to expire in 2024. These two patents appear to be the fundamental IP required to build an Illumina-style DNA sequencer. You may change or cancel your subscription or trial at any time online. (Reuters) - Illumina Inc and BGI Group's MGI Tech Co and Complete Genomics have settled U.S. litigation over their rival DNA-sequencing technology, the companies said Thursday. This week, the EPO Boards of Appeal rejected Illuminas appeal concerningEP 2 325 304(T2248/14-3.3.08), resulting in the loss of the patent. [1/2]A new office building housing genetic research company Illumina is shown in San Diego, California, U.S., May 30, 2018. PLEASE NOTE: A verification email will be sent to your address before you can access your trial. Get ready for your week with the weeks top business stories from San Diego and California, in your inbox Monday mornings. Mathys & Squire (London): Philippa Griffin, Strawman In July 2019, Illumina filed counterclaims alleging certain models of the BGISEQ and MGISEQ genetic sequencing instruments infringe three Illumina patents. The evidence also showed that BGI had copied numerous components of Illuminas technology, including its imaging buffer used in Illuminas sequencing-by-synthesis technology and infringed Illuminas patents related to that technology.. Access unmatched financial data, news and content in a highly-customised workflow experience on desktop, web and mobile. We use cookies and other technologies on our website. The listed products and their use are the subject of US Patent Nos. Analysis, Biological Data Law360 provides the intelligence you need to remain an expert and beat the competition. You can still enjoy your subscription until the end of your current billing period. Illumina, a publicly traded company based in San Diego with more than $3.2 billion in revenue in 2020, claimed that BGI and its subsidiaries willfully infringed five of its patents related to. Justia Patents Patents Assigned to Illumina Patents Assigned to Illumina LAMINATE FLUIDIC CIRCUIT FOR A FLUID CARTRIDGE Publication number: 20230048094 Abstract: An apparatus includes a fluid reservoir and a laminate fluidic circuit positioned above the fluid reservoir.